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Mail-order hereditary screening: what you ought to know

Dienstag, Dezember 24th, 2019

Mail-order hereditary screening: what you ought to know

Are these tests a choice that is wise?

10 years ago, businesses started developing saliva-based, at-home hereditary tests that provide people the capacity to find out about their hereditary characteristics. These tests began with ancestry information, then developed to incorporate faculties (such as for instance hair loss and locks color), predispositions for health issues (such as for instance Parkinson’s condition and cancer of the breast), and reactions to prescription that is certain. These “direct-to-consumer” (DTC) tests provide fast, cheap hereditary assessment without the need to consult well a physician… But is this a choice that is wise? And exactly how if the outcomes be interpreted and used?

Understand the restrictions: mail-order tests are neither comprehensive nor definitive

In March 2018, the usa Food and Drug management authorized DTC business 23andMe to report on dangers linked to the BRCA2 and BRCA1 genes. These genes had been catapulted to popularity in 2013 by Angelina Jolie, whom exposed about her experience and choices that are preventative a carrier of a BRCA1 mutation. The BRCA1/2 genes are related to a risk that is high breast and ovarian cancer, and mildly increased dangers for any other cancers. It is crucial for just about any specific considering 23andMe specifically for the BRCA1/2 mutations to comprehend its restrictions.

23andMe only reports on three BRCA1/2 mutations which can be just observed in the Ashkenazi Jewish population. You can find, in reality, over a lot of other mutations when you look at the BRCA1 and BRCA2 genes which are strongly related all cultural backgrounds, also more than a dozen other genes connected with somewhat increased dangers for breast and/or ovarian cancer tumors. (mehr …)